A correlation between protein thermostability and resistance to proteolysis.

نویسندگان

  • R M Daniel
  • D A Cowan
  • H W Morgan
  • M P Curran
چکیده

The loss of activity due to proteolysis of purified L-asparaginase and beta-galactosidase from different sources correlates with the thermal instability of the enzymes. A similar correlation is found when populations of soluble proteins from micro-organisms grown at different temperatures are compared for proteolytic susceptibility and thermal stability. It is proposed that there is a general correlation between the thermostability of proteins and their resistance to proteolysis.

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عنوان ژورنال:
  • The Biochemical journal

دوره 207 3  شماره 

صفحات  -

تاریخ انتشار 1982